HELPFUL RESOURCES

MedlinePlus: Infectious Diseases

National Institute of Allergy and Infectious Diseases

CDC's Emerging Infectious Diseases

CDC on Healthcare-Associated Infections

CDC Travel and Outbreak Notices

Morbidity and Mortality Weekly Resources

Infectious Diseases: Information from the World Health Organization

JOURNAL SCAN

Behavior Disorder After Encephalitis Caused by Dengue

psychiatryonline.org - 11/30/13

To the Editor: It has been reported that dengue is known as the most frequent human arboviral infection in the world, with 50 million cases per year and 2.5-to-3 million people at risk of contamination, estimated by OMS.¹ Co-circulation of the four types of dengue viruses and expansion of the dengue epidemic gave rise to infection enhancement and a big expansion of clinical aspects of the d

Antidepressant Activity of Linezolid

psychiatryonline.org - 11/30/13

To the Editor: Linezolid is an antibiotic approved for use in cases of infection by highly-resistant bacteria. It has weak activity as an inhibitor of monoamine oxidase.¹ It was reported in 2001 to be associated with a case of serotonin syndrome.² The association of linezolid with serotonin syndrome has been replicated, and it is now accepted pr

The Glucocorticoid Antagonist RU-486 Suppresses HIV Infectivity and Replication

psychiatryonline.org - 11/30/13

The effects of RU-486, a glucocorticoid antagonist, on HIV infection and replication in depressed and nondepressed women were studied using ex vivo models of HIV infection. RU-486 treatment of cells decreased HIV reverse transcriptase activity of monocyte-derived macrophages in a model of acute infectivity. RU-486 also decreased HIV viral replication in the chronically-infected T-cell line ACH-2, but not in the promonocyte cell line U1

Transmission of carcinogenic human papillomavirus types from mother to child: a meta-analysis of published studies

journals.lww.com - 4/30/13

Currently, human papillomavirus (HPV) research focuses on HPV infection in adults and sexual transmission. Data on HPV infection in children are slowly becoming available. It is a matter of debate whether mother-to-child transmission of HP

Usefulness of Intracardiac Echocardiography for the Diagnosis of Cardiovascular Implantable Electronic DeviceRelated Endocarditis

Content.onlinejacc.org - 4/2/13

Objectives

The goal of this study was to compare transesophageal echocardiography (TEE) and intracardiac echocardiography (ICE) for the diagnosis of cardiac devicerelated endocarditis (CDI).

Background

The diagnosis of infective endocarditis (IE) was established by using the modified Duke criteria based mainly on echocardiography and blood culture results. No previous studies have compared ICE with TEE for the diagno

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GUIDELINES

Guide to Clinical Preventive Services, 2010-2011: Section 2 (continued)

www.ahrq.gov - 8/31/10

Reviews the evidence for and against hundreds of preventive health services, recommending tests, and counseling interventions when evidence exists that it is effective.

Guide to Clinical Preventive Services, 2010-2011: Appendix Table: Recommended Childhood and Adolescent Immunization Schedule

www.ahrq.gov - 8/31/10

Reviews the evidence for and against hundreds of preventive health services, recommending tests, and counseling interventions when evidence exists that it is effective.

Guide to Clinical Preventive Services, 2010-2011: Appendix Table: Recommended Immunization Schedule for Persons Aged 7-18 Years

www.ahrq.gov - 8/31/10

Reviews the evidence for and against hundreds of preventive health services, recommending tests, and counseling interventions when evidence exists that it is effective.

Guide to Clinical Preventive Services, 2010-2011

www.ahrq.gov - 8/31/10

Reviews the evidence for and against hundreds of preventive health services, recommending tests, and counseling interventions when evidence exists that it is effective.

Guide to Clinical Preventive Services, 2010-2011: Appendix Figure 1: Recommended Adult Immunization Schedule, by Vaccine and Age Group

www.ahrq.gov - 8/31/10

Reviews the evidence for and against hundreds of preventive health services, recommending tests, and counseling interventions when evidence exists that it is effective.

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Infections in Medicine Archive »

NEWS

Americans Miss Mark on Many Healthy Behaviors (CME/CE)

MedPage Today - 5/24/13

(MedPage Today) -- When it comes to eating, drinking, and smoking, Americans may be overdoing it, but they get enough sleep, according to a CDC report.

Lab Notes: Doubt Cast on Alzheimer's Tx

MedPage Today - 5/24/13

(MedPage Today) -- Four groups said they could not replicate last year's electrifying finding that a cancer drug cleared beta amyloid plaques from the brains of mice. Also this week: nanoparticles as a next-gen flu vaccine.

APA Members Give DSM-5 Cautious Thumbs-Up

MedPage Today - 5/24/13

SAN FRANCISCO (MedPage Today) -- Members of the American Psychiatric Association got their first look at DSM-5 at the association's annual meeting here this week and shared their reactions with MedPage Today.

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JOURNALS: NOSOCOMIAL PNEUMONIA

One year outcomes in patients with acute lung injury randomised to initial trophic or full enteral feeding: prospective follow-up of EDEN randomised trial | BMJ

www.bmj.com - 3/19/13

AbstractObjective To evaluate the effect of initial low energy permissive underfeeding (trophic feeding) versus full energy enteral feeding (full feeding) on physical function and secondary outcomes in patients with acute lung injury.Design Prospective longitudinal follow-up evaluation of the NHLBI ARDS Clinical Trials Networks EDEN trialSetting 41hospitals in the United States.Participants 525 patients with acute lung injury.Interventions Randomised assignment to trophic or full feeding fo

First outbreak of nosocomial Legionella infection in term neonates caused by a cold mist ultrasonic humidifier

cid.oxfordjournals.org - 3/19/13

A cold mist humidifier in a nursery caused the first outbreak of nosocomial Legionellosis in term neonates. Legionella pneumophila serogroups 3 and 1 infected 28% of exposed neonates causing severe pneumonia or milder atypical symptoms, conferring a 33% overall mortality.

Effect of 10-Valent Pneumococcal Vaccine on Pneumonia among Children, Brazil

wwwnc.cdc.gov - 3/13/13

Pneumonia is most problematic for children in developing countries. In 2010, Brazil introduced a 10-valent pneumococcal conjugate vaccine (PCV10) to its National Immunization Program. To assess the vaccines effectiveness for preventing pneumonia, we analyzed rates of hospitalization among children 224 months of age who had pneumonia from all causes from January 2005 through August 2011. We used data from the National Hospitalization Information System to conduct an interrupted time-series analysis f

PLOS ONE: The Efficacy and Safety of Linezolid and Glycopeptides in the Treatment of Staphylococcus aureus Infections

www.plosone.org - 3/5/13

PLOS ONE: an inclusive, peer-reviewed, open-access resource from the PUBLIC LIBRARY OF SCIENCE. Reports of well-performed scientific studies from all disciplines freely available to the whole world.

Annals of Internal Medicine | NursePatient Ratios as a Patient Safety Strategy: A Systematic Review

annals.org - 3/4/13

0. Search. Email. American College of Physicians. You must be logged in as an individual user to share content. Copyright in the material you requested is held by American College Of Physicians ( unless otherwise noted). This email ability is

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JOURNALS: PEDIATRIC INFECTIONS

Trends in life expectancy in Europe: one big explanation or many small ones?

researchonline.lshtm.ac.uk -

2013). Trends in life expectancy in Europe: one big explanation or many small ones? ... View statistics for Trends in life expectancy in Europe one big explanation or many small ones.

Ragged Fortunes and Swashbuckling Thrillers; Or, Recreating the Victorian in Young Adult Fiction 1985-2011

researcharchive.vuw.ac.nz -

Ragged Fortunes and Swashbuckling Thrillers; Or, Recreating the Victorian in Young Adult Fiction 1985-2011.

James Macandrew of Otago: Slippery Jim or A Leader Staunch and True?

researcharchive.vuw.ac.nz -

James Macandrew of Otago: Slippery Jim or A Leader Staunch and True?

Risk of Fetal Death after Pandemic Influenza Virus Infection or Vaccination.

researchonline.lshtm.ac.uk -

Background During the 2009 influenza A (H1N1) pandemic, pregnant women were at risk for severe influenza illness. This concern was complicated by questions about vaccine safety in pregnant women that were raised by anecdotal reports of fetal deaths after vaccination. Methods We explored the safety of influenza vaccination of pregnant women by linking Norwegian national registries and medical consultation data to determine influenza diagnosis, vaccination status, birth outcomes, and background information

The effectiveness of mobile-health technology-based health behaviour change or disease management interventions for health care consumers: a systematic review.

researchonline.lshtm.ac.uk -

BACKGROUND Mobile technologies could be a powerful media for providing individual level support to health care consumers. We conducted a systematic review to assess the effectiveness of mobile technology interventions delivered to health care consumers. METHODS AND FINDINGS We searched for all controlled trials of mobile technology-based health interventions delivered to health care consumers using MEDLINE, EMBASE, PsycINFO, Global Health, Web of Science, Cochrane Library, UK NHS HTA (Jan 1990-Sept 2010).

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MEDLINE

Risk of fetal death after pandemic influenza virus infection or vaccination.

pubmed.gov - 1/23/13

During the 2009 influenza A (H1N1) pandemic, pregnant women were at risk for severe influenza illness. This concern was complicated by questions about vaccine safety in pregnant women that were raised by anecdotal reports of fetal deaths after vaccination.|We explored the safety of influenza vaccination of pregnant women by linking Norwegian national registries and medical consultation data to determine influenza diagnosis, vaccination status, birth outcomes, and background information for pregnant women before, during, and after the pandemic. We used Cox regression models to estimate hazard ratios for fetal death, with the gestational day as the time metric and vaccination and pandemic exposure as time-dependent exposure variables.|There were 117,347 eligible pregnancies in Norway from 2009 through 2010. Fetal mortality was 4.9 deaths per 1000 births. During the pandemic, 54% of pregnant women in their second or third trimester were vaccinated. Vaccination during pregnancy

Prospects for treatment of latent HIV.

pubmed.gov - 12/31/12

Recent advances in antiretroviral therapy (ART) have drastically improved the quality of life for people with HIV infection. However, owing to the persistence of latent HIV in the presence of therapy, patients must remain on therapy indefinitely. Currently, the solution to the HIV pandemic rests on the prevention of new infections and many decades of ART for the steadily expanding number of people infected worldwide. ART is costly, requires ongoing medical care, and can have side effects, thereby preventing its universal availability. Therefore, to escape the ironic burdens of therapy, efforts have begun to develop treatments for latent HIV infection. Current approaches propose either complete eradication of infection or induction of a state of stringent control over viral replication without ART. This review will discuss these strategies in detail and their potential for clinical development.

Individual and network factors associated with prevalent hepatitis C infection among rural Appalachian injection drug users.

pubmed.gov - 12/31/12

We determined the factors associated with hepatitis C (HCV) infection among rural Appalachian drug users.|This study included 394 injection drug users (IDUs) participating in a study of social networks and infectious disease risk in Appalachian Kentucky. Trained staff conducted HCV, HIV, and herpes simplex-2 virus (HSV-2) testing, and an interviewer-administered questionnaire measured self-reported risk behaviors and sociometric network characteristics.|The prevalence of HCV infection was 54.6% among rural IDUs. Lifetime factors independently associated with HCV infection included HSV-2, injecting for 5 or more years, posttraumatic stress disorder, injection of cocaine, and injection of prescription opioids. Recent (past-6-month) correlates of HCV infection included sharing of syringes (adjusted odds ratio = 2.24; 95% confidence interval = 1.32, 3.82) and greater levels of eigenvector centrality in the drug network.|One factor emerged that was potentially unique to rural IDUs: the

Epidemiology of 2009 pandemic influenza A virus subtype H1N1 among Kenyans aged 2 months to 18 years, 2009-2010.

pubmed.gov - 12/14/12

The US Army Medical Research Unit-Kenya (USAMRU-K) conducts surveillance for influenza-like illness (ILI) in Kenya. We describe the temporal and geographic progression of A(H1N1)pdm09 as it emerged in Kenya and characterize the outpatient population with A(H1N1)pdm09 infection.|We included patients with ILI aged 2 months to 18 years enrolled during June 2009-August 2010. Respiratory specimens were tested by real-time reverse-transcription polymerase chain reaction for influenza virus. Patients with A(H1N1)pdm09 infection were compared to those with seasonal influenza A virus infection and those with ILI who had no virus or a virus other than influenza virus identified (hereafter, "noninfluenza ILI").|Of 4251 patients with ILI, 193 had laboratory-confirmed A(H1N1)pdm09 infection. The first pandemic influenza case detected by USAMRU-K surveillance was in August 2009; peak activity nationwide occurred during October-November 2009. Patients with A(H1N1)pdm09 infection were more likely to

Influenza surveillance among children with pneumonia admitted to a district hospital in coastal Kenya, 2007-2010.

pubmed.gov - 12/14/12

Influenza data gaps in sub-Saharan Africa include incidence, case fatality, seasonal patterns, and associations with prevalent disorders.|Nasopharyngeal samples from children aged <12 years who were admitted to Kilifi District Hospital during 2007-2010 with severe or very severe pneumonia and resided in the local demographic surveillance system were screened for influenza A, B, and C viruses by molecular methods. Outpatient children provided comparative data.|Of 2002 admissions, influenza A virus infection was diagnosed in 3.5% (71), influenza B virus infection, in 0.9% (19); and influenza C virus infection, in 0.8% (11 of 1404 tested). Four patients with influenza died. Among outpatients, 13 of 331 (3.9%) with acute respiratory infection and 1 of 196 without acute respiratory infection were influenza positive. The annual incidence of severe or very severe pneumonia, of influenza (any type), and of influenza A, was 1321, 60, and 43 cases per 100,000 <5 years of age, respectively. Peak

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CLINICAL TRIALS IN INFECTIONS

Modulating the Alveolar Milieu to Enhance Resolution of Fibrotic Lung Injury

pats.atsjournals.org - 7/14/12

Fibrotic lung injury is often attributed to a myriad of factors, including environmental exposure, age, genetic predisposition, epigenetics, coexisting conditions, acute lung injury, and viral infection. No effective therapies, other than lung transplantation, have proven effective against lung fibrosis. Loss of cellular homeostasis mechanisms in alveolar epithelial type I cells and any inability of type II progenitor cells to resist and repair epithelial injury are indicators that impaired response t

Interleukin-15 and Influenza Virus Infection in a Mouse Model of Chronic Obstructive Pulmonary Disease

pats.atsjournals.org - 4/29/12

Pharmacotherapeutic Approaches to Preventing Acute Exacerbations of Chronic Obstructive Pulmonary Disease

pats.atsjournals.org - 8/3/11

The significance of acute exacerbations in chronic obstructive pulmonary disease (AECOPDs) is increasingly appreciated. AECOPDs result in significant morbidity and mortality and are a significant driver of health care costs. Frequent AECOPDs are associated with poor quality of life and more rapid decline in lung function. As such, reducing their frequency or severity is a key paradigm of COPD therapy. Bronchodilators alone and in combination with inhaled corticosteroids are the current standards of ca

Genetic Factors and Interrelationships for Cancer Risk-Related Behaviors and Complex Traits

www.clinicaltrials.gov - 11/2/99

Conditions: AcquiredImmunodeficiencySyndrome; Alcoholism; HIVInfection; Neoplasm; Smoking
Intervention:
Sponsor: NationalCancerInstitute(NCI)
Completed - verified July 2004

A Study of Atvogen in Healthy Volunteers and HIV-Infected Patients Who Have No Symptoms of Infection

www.clinicaltrials.gov - 11/1/99

Condition: HIVInfections
Intervention: Drug:Ampligen
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Completed - verified August 1991

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FROM PHYSICIANS PRACTICE

Five Steps to Improving Patient Access
Judy Capko, May 21, 2013
Patient access is getting increased attention through reform initiatives. Here are five steps you can take to make sure patients get appropriate access to care in your office.

Growing HIPAA Threat – Ignore Windows XP at Your Own Peril
Marion K. Jenkins, May 21, 2013
Chances are good that you have some major ticking software time bombs lurking in your medical practice's computer environment, namely Windows XP and Server 2003.

Finding Physician Work-Life Balance in the Small Moments
Jennifer Frank, MD, May 21, 2013
At my practice and at home, things are always busy. There's laundry or homework, or a patient with needs.

Three Areas to Reduce Costs at Your Medical Practice
Greg Mertz, May 19, 2013
By taking a hard look at reducing costs for staffing, overhead, and technology at your medical practice, you may see increased physician compensation.

Dos and Don’ts for Starting a Physician Blog
Michael Woo-Ming, MD, May 18, 2013
Starting a physician blog can provide your medical practice with marketing benefits, but it's important to do it right.

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SEARCHMEDICA NEWS

Campylobacter Bacteremia: Not What You Think?

December 7, 2011

FEATURED SEARCH: proteobacteria clsi

Commonly, bacteremia with Campylobacteria, the most common bacterial enteritis in developed countries, is diagnosed in older immunocompromised adults and is seen as a grave and threatening development. But this recent nationwide study in Finland (where reporting of bacteremia is mandatory) paints quite a different picture. The typical Finnish patient with this malady is “a moderately young and healthy man,” the researchers found, who recovers easily irrespective of whether he receives the appropriate antimicrobial.

RESULT: A Nationwide Study of Campylobacter jejuni and Campylobacter coli Bacteremia in Finland Over a 10-Year Period, 1998–2007, With Special Reference to Clinical Characteristics and Antimicrobial Susceptibility
Clinical Infectious Diseases | Oct 15, 2011 (FREE FULL TEXT)

Campylobacter is frequently found among HIV-infected patients. But with the introduction of highly active antiretroviral therapy (HAART) in the late 1990s, Campylobacter bacteremia can no longer be considered a significant disease of HIV-positive patients, according to a Spanish study from 1985-2007. In the HAART era, debilitating diseases such as chronic obstructive pulmonary disease have emerged as the chief predisposing conditions.

RESULT: Campylobacter bacteremia: clinical characteristics, incidence, and outcome over 23 years
Medicine (PubMed) | Sep 10, 2010 (Free abstract. Full text $49)

MANAGE YOUR PRACTICE

Getting the Most out of Your Advertising Dollar

Physicians Practice - 5/24/13

Getting the Most out of Your Advertising Dollar

Blog | May 25, 2013 | Marketing, Patient Relations

In the competition with hospitals, independent must use their limited advertising budgets wisely

Five Ways to Streamline Patient Appointments

Physicians Practice - 5/24/13

Five Ways to Streamline Patient Appointments

Blog | May 25, 2013 | EHR, Medical Billing & Collections, Operations, Patient Relations, Payers

By P.j. Cloud-moulds

When you find your medical practice constantly behind, unorganized, and frazzled at the end of every day, maybe it's time to take a look at your work flow.

Congress Could Ease International Medical Graduate Restrictions

Physicians Practice - 5/24/13

Congress Could Ease International Medical Graduate Restrictions

Blog | May 24, 2013 | Healthcare Careers, Healthcare Reform, Law & Malpractice, Recruitment

By Aubrey Westgate

Research shows the value of international medical graduates practicing in the U.S. and now Congress wants to help increase their numbers.

Healthcare Reform is Changing the Landscape of Medicine

Physicians Practice - 5/24/13

Healthcare Reform is Changing the Landscape of Medicine

Blog | May 24, 2013 | Healthcare Careers, Healthcare Reform, Patients, Physician Compensation

By J. Scott Litton, Jr., MD

Physicians will likely have a hard time embracing future changes under the Affordable Care Act as the current effects are less than desirable already.

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