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JOURNAL SCAN
BMC Immunology | Abstract | Variation in the IL1B, TNF and IL6 genes and individual susceptibility to prosthetic joint infection
www.biomedcentral.com - 5/8/12
Prosthetic joint infection (PJI) is an important failure mechanism of total joint arthroplasty (TJA). Here we examine whether the particular genetic variants can lead to increased susceptibility to PJI development.|Prosthetic joint infection (PJI) is an important failure mechanism of total joint arthroplasty (TJA). Here we examine whether the particular genetic variants can lead to increased susceptibility to PJI development.
Urinary Tract Infection, May 2, 2012, Torpy et al. 307 (17): 1877 JAMA
jama.ama-assn.org - 5/2/12
Welcome. JAMA Patient Page. JAMA. 2012; 307( 17): 1877.doi: 10.1001/jama.2012.3885. Urinary Tract Infection. ... Blood in the urine. Foul-smelling urine. Fever may be present in cases of more serious infection.
PLoS ONE: Surveillance Length and Validity of Benchmarks for Central Line-Associated Bloodstream Infection Incidence Rates in Intensive Care Units
www.plosone.org - 5/7/12
PLoS ONE: an inclusive, peer-reviewed, open-access resource from the PUBLIC LIBRARY OF SCIENCE. Reports of well-performed scientific studies from all disciplines freely available to the whole world.
Evaluation of the national Cleanyourhands campaign to reduce Staphylococcus aureus bacteraemia and Clostridium difficile infection in hospitals in England and Wales by improved hand hygiene: four year, prospective, ecological, interrupted time series stu
www.bmj.com - 5/3/12
AbstractObjective To evaluate the impact of the Cleanyourhands campaign on rates of hospital procurement of alcohol hand rub and soap, report trends in selected healthcare associated infections, and investigate the association between infections and procurement.Design Prospective, ecological, interrupted time series study from 1 July 2004 to 30 June 2008.Setting 187 acute trusts in England and Wales.Intervention Installation of bedside alcohol hand rub, materials promoting hand hygiene and institutional e
Arch Intern Med
archinte.ama-assn.org - 5/7/12
Archives of Internal Medicine, a bi-monthly professional medical journal published by the American Medical Association, publishes original peer-reviewed research articles on internal medicine topics

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GUIDELINES
Guide to Clinical Preventive Services, 2010-2011: Section 2 (continued)
www.ahrq.gov - 9/1/10
Reviews the evidence for and against hundreds of preventive health services, recommending tests, and counseling interventions when evidence exists that it is effective.
Guide to Clinical Preventive Services, 2010-2011
www.ahrq.gov - 9/1/10
Reviews the evidence for and against hundreds of preventive health services, recommending tests, and counseling interventions when evidence exists that it is effective.
Guide to Clinical Preventive Services, 2010-2011: Appendix Figure 1: Recommended Adult Immunization Schedule, by Vaccine and Age Group
www.ahrq.gov - 9/1/10
Reviews the evidence for and against hundreds of preventive health services, recommending tests, and counseling interventions when evidence exists that it is effective.
Guide to Clinical Preventive Services, 2010-2011: Appendix Table: Recommended Immunization Schedule for Persons Aged 7-18 Years
www.ahrq.gov - 9/1/10
Reviews the evidence for and against hundreds of preventive health services, recommending tests, and counseling interventions when evidence exists that it is effective.
Guide to Clinical Preventive Services, 2010-2011: Appendix Table: Recommended Childhood and Adolescent Immunization Schedule
www.ahrq.gov - 9/1/10
Reviews the evidence for and against hundreds of preventive health services, recommending tests, and counseling interventions when evidence exists that it is effective.

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Infections in Medicine Archive »

 
NEWS
CDC Lowers the Bar for 'Lead Poisoning'
MedPage Today - 5/16/12
(MedPage Today) -- The CDC has lowered by half the danger threshold for lead levels in children's blood, one of more than a dozen advisory committee recommendations that the agency has accepted in principle.
Azithromycin May Up Risk of Cardiac Death (CME/CE)
MedPage Today - 5/16/12
(MedPage Today) -- Use of a common antibiotic, azithromycin, appears to significantly increase the risk of sudden cardiac death when compared with no antibiotic treatment, according to analysis of data from Medicaid patients.
FDA Delays New Sunscreen Labeling Rules
MedPage Today - 5/16/12
?WASHINGTON (MedPage Today) -- The FDA has granted sunscreen manufacturers a 6-month extension to comply with new labeling rules in order to avoid having mislabeled sunscreens on the shelves this summer or a product shortage.

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JOURNALS: NOSOCOMIAL PNEUMONIA
PLoS ONE: Molecular Analysis and Risk Factors for Escherichia coli Producing Extended-Spectrum -Lactamase Bloodstream Infection in Hematological Malignancies
www.plosone.org - 4/23/12
PLoS ONE: an inclusive, peer-reviewed, open-access resource from the PUBLIC LIBRARY OF SCIENCE. Reports of well-performed scientific studies from all disciplines freely available to the whole world.
Paediatric hospital-acquired bacteraemia in developing countries : The Lancet
www.thelancet.com - 4/21/12
Paediatric hospital-acquired bacteraemia in developing countries. By - Martin Wolkewitz, Susanna Di Termini, Ben Cooper, Joerg Meerpohl, Martin Schumacher
Pseudomonas aeruginosa Respiratory Tract Infections Associated with Contaminated Ultrasound Gel Used for Transesophageal Echocardiography Michigan, December 2011January 2012
www.cdc.gov - 4/20/12
aeruginosa. Surveillance for nosocomial infection at BHS is driven by results of clinical microbiology cultures. ... Of the 16 patients identified during the outbreak, two had pneumonia, five had tracheobronchitis, and nine had respiratory tract
PLoS ONE: Sharing More than Friendship Nasal Colonization with Coagulase-Positive Staphylococci (CPS) and Co-Habitation Aspects of Dogs and Their Owners
www.plosone.org - 4/18/12
PLoS ONE: an inclusive, peer-reviewed, open-access resource from the PUBLIC LIBRARY OF SCIENCE. Reports of well-performed scientific studies from all disciplines freely available to the whole world.
PLoS ONE: Agreement among Health Care Professionals in Diagnosing Case Vignette-Based Surgical Site Infections
www.plosone.org - 4/17/12
PLoS ONE: an inclusive, peer-reviewed, open-access resource from the PUBLIC LIBRARY OF SCIENCE. Reports of well-performed scientific studies from all disciplines freely available to the whole world.

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JOURNALS: PEDIATRIC INFECTIONS
Otitis Media
topics.searchmedica.com - 5/7/12
15. 16. 17. 18. 19. 20. of 20. First Previouswww.plosone.org. - 4/30/12. ... PLoS ONE Otitis Media in a New Mouse Model for CHARGE Syndrome with a Deletion in the Chd7 Gene.
What are complex or multifactorial disorders?
ghr.nlm.nih.gov - 5/7/12
A service of the U.S. National Library of Medicine. Handbook. What are complex or multifactorial disorders? ... Conditions caused by many contributing factors are called complex or multifactorial disorders.
PLoS ONE: Microbe-Specific C3b Deposition in the Horseshoe Crab Complement System in a C2/Factor B-Dependent or
www.plosone.org - 5/7/12
PLoS ONE: an inclusive, peer-reviewed, open-access resource from the PUBLIC LIBRARY OF SCIENCE. Reports of well-performed scientific studies from all disciplines freely available to the whole world.
PLoS ONE: Screening Estrogenic Activities of Chemicals or Mixtures In Vivo Using Transgenic (cyp19a1b-GFP) Zebrafish Embryos
www.plosone.org - 5/7/12
PLoS ONE: an inclusive, peer-reviewed, open-access resource from the PUBLIC LIBRARY OF SCIENCE. Reports of well-performed scientific studies from all disciplines freely available to the whole world.
BMJ
www.bmj.com - 5/2/12
NotesCite this as: BMJ 2012;344:e3043

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MEDLINE
Effect of a cash transfer programme for schooling on prevalence of HIV and herpes simplex type 2 in Malawi: a cluster randomised trial.
pubmed.gov - 4/7/12
Lack of education and an economic dependence on men are often suggested as important risk factors for HIV infection in women. We assessed the efficacy of a cash transfer programme to reduce the risk of sexually transmitted infections in young women.|In this cluster randomised trial, never-married women aged 13-22 years were recruited from 176 enumeration areas in the Zomba district of Malawi and randomly assigned with computer-generated random numbers by enumeration area (1:1) to receive cash payments (intervention group) or nothing (control group). Intervention enumeration areas were further randomly assigned with computer-generated random numbers to conditional (school attendance required to receive payment) and unconditional (no requirements to receive payment) groups. Participants in both intervention groups were randomly assigned by a lottery to receive monthly payments ranging from US$1 to $5, while their parents were independently assigned with computer-generated random numbers
What's new in respiratory infections and tuberculosis 2008-2010.
pubmed.gov - 4/2/12
Over the past few years there have been an increasing number of research articles published in Thorax on respiratory tract infections (including tuberculosis) affecting children and adults. Although these articles cover a wide variety of areas, several broad themes can be discerned. These include greater interest in viral respiratory infections (partially stimulated by the recent influenza A pandemic), improved characterisation of who is at risk of community-acquired pneumonia and mycobacterial infection, research into better diagnostics and attempts to develop new or improved scoring scales for a range of respiratory infection syndromes. There have also been a limited number of articles on how to manage patients with respiratory infection, including describing the efficacy of prevention by vaccination. Overall, there has been a discernible emphasis on transferring advances in clinical science to actual clinical practice, with several papers using molecular methodologies or measuring
Spatial dynamics of airborne infectious diseases.
pubmed.gov - 3/21/12
Disease outbreaks, such as those of Severe Acute Respiratory Syndrome in 2003 and the 2009 pandemic A(H1N1) influenza, have highlighted the potential for airborne transmission in indoor environments. Respirable pathogen-carrying droplets provide a vector for the spatial spread of infection with droplet transport determined by diffusive and convective processes. An epidemiological model describing the spatial dynamics of disease transmission is presented. The effects of an ambient airflow, as an infection control, are incorporated leading to a delay equation, with droplet density dependent on the infectious density at a previous time. It is found that small droplets (0.4m) generate a negligible infectious force due to the small viral load and the associated duration they require to transmit infection. In contrast, larger droplets (4m) can lead to an infectious wave propagating through a fully susceptible population or a secondary infection outbreak for a localized susceptible
Risk of transmission of H1N1 influenza by solid organ transplantation in the United Kingdom.
pubmed.gov - 3/15/12
Concern that pandemic H1N1 swine influenza could be transmitted by solid organ transplantation led to the publication of guidance advising screening of donors, restriction of use of organs under certain conditions, and prophylaxis of recipients. We have reviewed the outcomes for cases of solid organ graft recipients from H1N1 influenza-positive donors in the United Kingdom up to May 2010.|The Organ Donation and Transplantation Directorate supplied a list of five known H1N1 influenza-positive donors, one of whom died from active H1N1 infection. Transplanting teams were contacted to gain information on clinical outcomes.|Thirteen organs were grafted from the donors. None of the 13 recipients developed suspected or confirmed H1N1 influenza. There was variable use of antiviral chemoprophylaxis and screening of recipients for H1N1 influenza.|No cases of transplant-related H1N1 influenza transmission were demonstrated in this series. It remains prudent that transplanting teams have a high
Oseltamivir use in infants under one year of age: are there still unanswered questions?
pubmed.gov - 3/8/12
The influenza A (H1N1) virus responsible for the 2009 pandemic follows a more severe course in children, thus increasing the need for hospitalization. On the other hand, during the first weeks of the pandemic, use of oseltamivir (Tamiflu) in children was restricted, and it was not yet approved for use in children younger than one year of age because of the lack of adequate safety and efficacy data and because of concerns regarding central nervous system (CNS) toxicity in newborn rats. However, citing a state of emergency, conditional approval was granted first in the United States, then Europe and finally in Turkey. The main aim of this study was to share our experience with oseltamivir in 35 patients less than one year of age during the 2009 H1N1 pandemic. A total of 35 infants (21 boys, 14 girls; mean age: 160 days [24-335]) were treated during the study period. Six patients required hospitalization, five of whom (14.2%) had an underlying chronic disorder. During the pandemic, we

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CLINICAL TRIALS IN INFECTIONS
A Study of Atvogen in Healthy Volunteers and HIV-Infected Patients Who Have No Symptoms of Infection
www.clinicaltrials.gov - 11/2/12
Condition: HIVInfections
Intervention: Drug:Ampligen
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Completed - verified August 1991
A Multi-Center Clinical Trial To Evaluate Azidothymidine (AZT) in the Treatment of Human Immunodeficiency Virus (HIV) Infection in Patients With AIDS Post First Episode PCP
www.clinicaltrials.gov - 11/2/12
Condition: HIVInfections
Intervention: Drug:Zidovudine
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Completed - verified September 2002
Evaluation of the Association of Polymorphisms in the Innate Immune System With the Risk for Cryptococcus Neoformans Infection in Patients Not Infected With HIV and Complications Associated With Cryptococcus Neoformans Infection
www.clinicaltrials.gov -
Full Text View. Evaluation of the Association of Polymorphisms in the Innate Immune System With the Risk for Cryptococcus Neoformans Infection in Patients Not Infected With HIV and Complications Associated With ... We hypothesize that subtle differences
Evaluation of the Association of Polymorphisms in the Innate Immune System With the Risk for Blastomycosis Dermatitidis Infection in Patients Not Infected With HIV and Complications Associated With Blastomycosis Dermatitidis Infection
www.clinicaltrials.gov -
Full Text View. Evaluation of the Association of Polymorphisms in the Innate Immune System With the Risk for Blastomycosis Dermatitidis Infection in Patients Not Infected With HIV and Complications Associated With ... We hypothesize that subtle
Specimen Collections From Patients With HIV Infection, KSHV Infection, Viral-Related Pre-malignant Lesions and Cancer
www.clinicaltrials.gov -
infection, infection with Kaposi's sarcoma associated herpesvirus ( KSHV), infection with other oncogenic viruses, or cancer. ... Detailed Description:. BACKGROUND: A number of important scientific advances can be made through the study of blood, bone

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FROM PHYSICIANS PRACTICE
Physician Performance Goals Are Great, But Balance Is More Realistic
Jennifer Frank, MD,  May 15, 2012
Performance measurements for physicians are well-intentioned and get me to rethink how I practice. But in the end I won't make the goals, so I'll have to go with balance over perfection.
Designing the Perfect Business Card for Your Medical Practice
C. Noel Henley, MD,  May 11, 2012
Does your business card say anything substantive about the valuable work you do in your practice? Here’s how to re-design your next business card for maximum impact and engagement.
Registered Nurses an Ideal Fit for Primary Care Practices
Audrey "Christie" McLaughlin, RN,  May 10, 2012
Here are four good reasons to hire a registered nurse for your primary care practice …maybe even instead of a medical assistant.
The Five Biggest Medical Practice Marketing Mistakes
James Doulgeris,  May 10, 2012
There are best practices to marketing your practice, but often, success is more about knowing what not to do. Here are the five most common pitfalls …and how to avoid them.
Can You Practice Medicine and Manage Your Practice?
Rosemarie Nelson,  May 9, 2012
Whether you practice alone, or in a group, if you're trying to see patients in this pay-for-volume environment and also run the business of your practice, you may be missing out on important opportunities.
 
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SEARCHMEDICA NEWS


SearchMedica News From a top search during the past week on SearchMedica
 

From Birds via Pigs to People: New Influenza Virus

January 18, 2012

FEATURED SEARCH TERM:   H1N1 symptoms


Increased vigilance against variant influenza is paying off. The CDC report below describes a small outbreak of a new influenza virus—a recombinant between the so-called swine flu and bird flu (H1N1) viruses—that affected 12 people in five states late last year, many of them children. One outbreak took place in a day care center. The report tells exactly how pork industry workers should protect themselves, and what a doctor should do in the case of a suspected infection. 

 

RESULT: Update: Influenza A (H3N2)v Transmission and Guidelines — Five States, 2011
MMWR | Dec 23, 2011 (FREE FULL TEXT)

 

Be prepared to begin spraying rather than jabbing against the flu. Animal studies show that aerosolized vaccine can elicit robust immune responses at the site of infection against respiratory pathogens such as influenza, according to authors from the NIH. Aerosolized vaccines would have the advantage of inducing local mucosal immune responses and, being both safer and more comfortable for patients, also more acceptable.
 

 

RESULT:Aerosolized Adenovirus-vectored Vaccine as an Alternative Vaccine Delivery
Method

Respiratory Research | Nov 21, 2011 (FREE FULL TEXT)


 

 

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MANAGE YOUR PRACTICE
The End-of-Day Report: Financial Control for Your Medical Practice
Physicians Practice - 5/16/12
If you are looking for a simple way to control your medical practice finances, here it is: the end-of-day report.
Permanent SGR 'Doc Fix,' Medicaid Reimbursement Increase Proposed
Physicians Practice - 5/16/12
Two proposals released last week could lead to higher physician reimbursement.
How to Close Your Medical Practice the Right Way
Physicians Practice - 5/16/12
Whether you've decided to retire, relocate, or retreat from practice, you can reduce the pain for your patients and staff by following these five guidelines.
Text Messaging and Patients: Benefits and Considerations
Physicians Practice - 5/16/12
As convenient as text messaging may be, there are certain issues for healthcare providers to consider when using any communication method with patients. Here are seven to consider.

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