FEATURED SEARCH TERM: ulcerative colitis
To the possible triggers of bowel inflammation, add unexpected reactions to cosmetic procedures. Ulcerative colitis was one of the adverse reactions to an illicit cosmetic procedure in Mexico. Injection of foreign substances, mostly oils, led the 50 women in this case study to develop autoimmune disease, as well as non-specific autoimmune manifestations, all of which fit the model of Autoimmune/inflammatory Syndrome Induced by Adjuvants (ASIA).
RESULT: Human adjuvant disease induced by foreign substances: a new model of ASIA (Shoenfeld's syndrome)
Journal of the American College of Cardiology | Jan 10, 2012 (FREE FULL TEXT)
On the other hand, intentionally inducing and studying the inflammatory reaction could lead to useful treatment insights. In this study, experimentally induced hookworm infections in human volunteers suppressed pro-inflammatory cytokine production in the gut. The only previous report of intentionally induced hookworms in humans was an attempt to treat ulcerative colitis with whipworm. These researchers suggest that manipulating the anti-hookworm response may inspire new therapies for inflammatory diseases.
RESULT: Characterising the Mucosal and Systemic Immune Responses to Experimental Human Hookworm Infection
PLoS Pathogens | Feb 9, 2012 (FREE FULL TEXT)
- Suspicious Skin Lesions and Secondary Syphilis
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- Herpes Simplex: Initial and Recurrent Infections