HELPFUL RESOURCES

MedlinePlus: Infectious Diseases

National Institute of Allergy and Infectious Diseases

CDC's Emerging Infectious Diseases

CDC on Healthcare-Associated Infections

CDC Travel and Outbreak Notices

Morbidity and Mortality Weekly Resources

Infectious Diseases: Information from the World Health Organization

JOURNAL SCAN

Behavior Disorder After Encephalitis Caused by Dengue

psychiatryonline.org - 11/30/13

To the Editor: It has been reported that dengue is known as the most frequent human arboviral infection in the world, with 50 million cases per year and 2.5-to-3 million people at risk of contamination, estimated by OMS.¹ Co-circulation of the four types of dengue viruses and expansion of the dengue epidemic gave rise to infection enhancement and a big expansion of clinical aspects of the d

Antidepressant Activity of Linezolid

psychiatryonline.org - 11/30/13

To the Editor: Linezolid is an antibiotic approved for use in cases of infection by highly-resistant bacteria. It has weak activity as an inhibitor of monoamine oxidase.¹ It was reported in 2001 to be associated with a case of serotonin syndrome.² The association of linezolid with serotonin syndrome has been replicated, and it is now accepted pr

The Glucocorticoid Antagonist RU-486 Suppresses HIV Infectivity and Replication

psychiatryonline.org - 11/30/13

The effects of RU-486, a glucocorticoid antagonist, on HIV infection and replication in depressed and nondepressed women were studied using ex vivo models of HIV infection. RU-486 treatment of cells decreased HIV reverse transcriptase activity of monocyte-derived macrophages in a model of acute infectivity. RU-486 also decreased HIV viral replication in the chronically-infected T-cell line ACH-2, but not in the promonocyte cell line U1

Transmission of carcinogenic human papillomavirus types from mother to child: a meta-analysis of published studies

journals.lww.com - 4/30/13

Currently, human papillomavirus (HPV) research focuses on HPV infection in adults and sexual transmission. Data on HPV infection in children are slowly becoming available. It is a matter of debate whether mother-to-child transmission of HP

Usefulness of Intracardiac Echocardiography for the Diagnosis of Cardiovascular Implantable Electronic DeviceRelated Endocarditis

Content.onlinejacc.org - 4/2/13

Objectives

The goal of this study was to compare transesophageal echocardiography (TEE) and intracardiac echocardiography (ICE) for the diagnosis of cardiac devicerelated endocarditis (CDI).

Background

The diagnosis of infective endocarditis (IE) was established by using the modified Duke criteria based mainly on echocardiography and blood culture results. No previous studies have compared ICE with TEE for the diagno

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GUIDELINES

Guide to Clinical Preventive Services, 2010-2011: Section 2 (continued)

www.ahrq.gov - 8/31/10

Reviews the evidence for and against hundreds of preventive health services, recommending tests, and counseling interventions when evidence exists that it is effective.

Guide to Clinical Preventive Services, 2010-2011: Appendix Table: Recommended Childhood and Adolescent Immunization Schedule

www.ahrq.gov - 8/31/10

Reviews the evidence for and against hundreds of preventive health services, recommending tests, and counseling interventions when evidence exists that it is effective.

Guide to Clinical Preventive Services, 2010-2011: Appendix Table: Recommended Immunization Schedule for Persons Aged 7-18 Years

www.ahrq.gov - 8/31/10

Reviews the evidence for and against hundreds of preventive health services, recommending tests, and counseling interventions when evidence exists that it is effective.

Guide to Clinical Preventive Services, 2010-2011

www.ahrq.gov - 8/31/10

Reviews the evidence for and against hundreds of preventive health services, recommending tests, and counseling interventions when evidence exists that it is effective.

Guide to Clinical Preventive Services, 2010-2011: Appendix Figure 1: Recommended Adult Immunization Schedule, by Vaccine and Age Group

www.ahrq.gov - 8/31/10

Reviews the evidence for and against hundreds of preventive health services, recommending tests, and counseling interventions when evidence exists that it is effective.

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Infections in Medicine Archive »

NEWS

A Little Estrogen Goes a Long Way in Preventing UTI (CME/CE)

MedPage Today - 6/19/13

(MedPage Today) -- Short-term estrogen therapy induced cellular changes in urothelium consistent with improved ability to fight off urinary tract infection, results from clinical and preclinical studies suggested.

CDC: Flu Shots Averted Millions of Cases (CME/CE)

MedPage Today - 6/19/13

(MedPage Today) -- Vaccination prevented between 1.1 million and 5 million cases of the flu per season over a 6-year period, according to new estimates.

New Coronavirus 'Eerily' Like SARS (CME/CE)

MedPage Today - 6/19/13

(MedPage Today) -- The novel coronavirus outbreak in the Middle East is eerily similar to SARS, according to an expert who was part of a team studying a cluster of cases in hospitals in Saudi Arabia.

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JOURNALS: NOSOCOMIAL PNEUMONIA

One year outcomes in patients with acute lung injury randomised to initial trophic or full enteral feeding: prospective follow-up of EDEN randomised trial | BMJ

www.bmj.com - 3/19/13

AbstractObjective To evaluate the effect of initial low energy permissive underfeeding (trophic feeding) versus full energy enteral feeding (full feeding) on physical function and secondary outcomes in patients with acute lung injury.Design Prospective longitudinal follow-up evaluation of the NHLBI ARDS Clinical Trials Networks EDEN trialSetting 41hospitals in the United States.Participants 525 patients with acute lung injury.Interventions Randomised assignment to trophic or full feeding fo

First outbreak of nosocomial Legionella infection in term neonates caused by a cold mist ultrasonic humidifier

cid.oxfordjournals.org - 3/19/13

A cold mist humidifier in a nursery caused the first outbreak of nosocomial Legionellosis in term neonates. Legionella pneumophila serogroups 3 and 1 infected 28% of exposed neonates causing severe pneumonia or milder atypical symptoms, conferring a 33% overall mortality.

Effect of 10-Valent Pneumococcal Vaccine on Pneumonia among Children, Brazil

wwwnc.cdc.gov - 3/13/13

Pneumonia is most problematic for children in developing countries. In 2010, Brazil introduced a 10-valent pneumococcal conjugate vaccine (PCV10) to its National Immunization Program. To assess the vaccines effectiveness for preventing pneumonia, we analyzed rates of hospitalization among children 224 months of age who had pneumonia from all causes from January 2005 through August 2011. We used data from the National Hospitalization Information System to conduct an interrupted time-series analysis f

PLOS ONE: The Efficacy and Safety of Linezolid and Glycopeptides in the Treatment of Staphylococcus aureus Infections

www.plosone.org - 3/5/13

PLOS ONE: an inclusive, peer-reviewed, open-access resource from the PUBLIC LIBRARY OF SCIENCE. Reports of well-performed scientific studies from all disciplines freely available to the whole world.

Annals of Internal Medicine | NursePatient Ratios as a Patient Safety Strategy: A Systematic Review

annals.org - 3/4/13

0. Search. Email. American College of Physicians. You must be logged in as an individual user to share content. Copyright in the material you requested is held by American College Of Physicians ( unless otherwise noted). This email ability is

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JOURNALS: PEDIATRIC INFECTIONS

Trends in life expectancy in Europe: one big explanation or many small ones?

researchonline.lshtm.ac.uk -

2013). Trends in life expectancy in Europe: one big explanation or many small ones? ... View statistics for Trends in life expectancy in Europe one big explanation or many small ones.

Ragged Fortunes and Swashbuckling Thrillers; Or, Recreating the Victorian in Young Adult Fiction 1985-2011

researcharchive.vuw.ac.nz -

Ragged Fortunes and Swashbuckling Thrillers; Or, Recreating the Victorian in Young Adult Fiction 1985-2011.

James Macandrew of Otago: Slippery Jim or A Leader Staunch and True?

researcharchive.vuw.ac.nz -

James Macandrew of Otago: Slippery Jim or A Leader Staunch and True?

Risk of Fetal Death after Pandemic Influenza Virus Infection or Vaccination.

researchonline.lshtm.ac.uk -

Background During the 2009 influenza A (H1N1) pandemic, pregnant women were at risk for severe influenza illness. This concern was complicated by questions about vaccine safety in pregnant women that were raised by anecdotal reports of fetal deaths after vaccination. Methods We explored the safety of influenza vaccination of pregnant women by linking Norwegian national registries and medical consultation data to determine influenza diagnosis, vaccination status, birth outcomes, and background information

The effectiveness of mobile-health technology-based health behaviour change or disease management interventions for health care consumers: a systematic review.

researchonline.lshtm.ac.uk -

BACKGROUND Mobile technologies could be a powerful media for providing individual level support to health care consumers. We conducted a systematic review to assess the effectiveness of mobile technology interventions delivered to health care consumers. METHODS AND FINDINGS We searched for all controlled trials of mobile technology-based health interventions delivered to health care consumers using MEDLINE, EMBASE, PsycINFO, Global Health, Web of Science, Cochrane Library, UK NHS HTA (Jan 1990-Sept 2010).

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MEDLINE

Risk of fetal death after pandemic influenza virus infection or vaccination.

pubmed.gov - 1/23/13

During the 2009 influenza A (H1N1) pandemic, pregnant women were at risk for severe influenza illness. This concern was complicated by questions about vaccine safety in pregnant women that were raised by anecdotal reports of fetal deaths after vaccination.|We explored the safety of influenza vaccination of pregnant women by linking Norwegian national registries and medical consultation data to determine influenza diagnosis, vaccination status, birth outcomes, and background information for pregnant women before, during, and after the pandemic. We used Cox regression models to estimate hazard ratios for fetal death, with the gestational day as the time metric and vaccination and pandemic exposure as time-dependent exposure variables.|There were 117,347 eligible pregnancies in Norway from 2009 through 2010. Fetal mortality was 4.9 deaths per 1000 births. During the pandemic, 54% of pregnant women in their second or third trimester were vaccinated. Vaccination during pregnancy

Prospects for treatment of latent HIV.

pubmed.gov - 12/31/12

Recent advances in antiretroviral therapy (ART) have drastically improved the quality of life for people with HIV infection. However, owing to the persistence of latent HIV in the presence of therapy, patients must remain on therapy indefinitely. Currently, the solution to the HIV pandemic rests on the prevention of new infections and many decades of ART for the steadily expanding number of people infected worldwide. ART is costly, requires ongoing medical care, and can have side effects, thereby preventing its universal availability. Therefore, to escape the ironic burdens of therapy, efforts have begun to develop treatments for latent HIV infection. Current approaches propose either complete eradication of infection or induction of a state of stringent control over viral replication without ART. This review will discuss these strategies in detail and their potential for clinical development.

Individual and network factors associated with prevalent hepatitis C infection among rural Appalachian injection drug users.

pubmed.gov - 12/31/12

We determined the factors associated with hepatitis C (HCV) infection among rural Appalachian drug users.|This study included 394 injection drug users (IDUs) participating in a study of social networks and infectious disease risk in Appalachian Kentucky. Trained staff conducted HCV, HIV, and herpes simplex-2 virus (HSV-2) testing, and an interviewer-administered questionnaire measured self-reported risk behaviors and sociometric network characteristics.|The prevalence of HCV infection was 54.6% among rural IDUs. Lifetime factors independently associated with HCV infection included HSV-2, injecting for 5 or more years, posttraumatic stress disorder, injection of cocaine, and injection of prescription opioids. Recent (past-6-month) correlates of HCV infection included sharing of syringes (adjusted odds ratio = 2.24; 95% confidence interval = 1.32, 3.82) and greater levels of eigenvector centrality in the drug network.|One factor emerged that was potentially unique to rural IDUs: the

Epidemiology of 2009 pandemic influenza A virus subtype H1N1 among Kenyans aged 2 months to 18 years, 2009-2010.

pubmed.gov - 12/14/12

The US Army Medical Research Unit-Kenya (USAMRU-K) conducts surveillance for influenza-like illness (ILI) in Kenya. We describe the temporal and geographic progression of A(H1N1)pdm09 as it emerged in Kenya and characterize the outpatient population with A(H1N1)pdm09 infection.|We included patients with ILI aged 2 months to 18 years enrolled during June 2009-August 2010. Respiratory specimens were tested by real-time reverse-transcription polymerase chain reaction for influenza virus. Patients with A(H1N1)pdm09 infection were compared to those with seasonal influenza A virus infection and those with ILI who had no virus or a virus other than influenza virus identified (hereafter, "noninfluenza ILI").|Of 4251 patients with ILI, 193 had laboratory-confirmed A(H1N1)pdm09 infection. The first pandemic influenza case detected by USAMRU-K surveillance was in August 2009; peak activity nationwide occurred during October-November 2009. Patients with A(H1N1)pdm09 infection were more likely to

Influenza surveillance among children with pneumonia admitted to a district hospital in coastal Kenya, 2007-2010.

pubmed.gov - 12/14/12

Influenza data gaps in sub-Saharan Africa include incidence, case fatality, seasonal patterns, and associations with prevalent disorders.|Nasopharyngeal samples from children aged <12 years who were admitted to Kilifi District Hospital during 2007-2010 with severe or very severe pneumonia and resided in the local demographic surveillance system were screened for influenza A, B, and C viruses by molecular methods. Outpatient children provided comparative data.|Of 2002 admissions, influenza A virus infection was diagnosed in 3.5% (71), influenza B virus infection, in 0.9% (19); and influenza C virus infection, in 0.8% (11 of 1404 tested). Four patients with influenza died. Among outpatients, 13 of 331 (3.9%) with acute respiratory infection and 1 of 196 without acute respiratory infection were influenza positive. The annual incidence of severe or very severe pneumonia, of influenza (any type), and of influenza A, was 1321, 60, and 43 cases per 100,000 <5 years of age, respectively. Peak

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CLINICAL TRIALS IN INFECTIONS

Modulating the Alveolar Milieu to Enhance Resolution of Fibrotic Lung Injury

pats.atsjournals.org - 7/14/12

Fibrotic lung injury is often attributed to a myriad of factors, including environmental exposure, age, genetic predisposition, epigenetics, coexisting conditions, acute lung injury, and viral infection. No effective therapies, other than lung transplantation, have proven effective against lung fibrosis. Loss of cellular homeostasis mechanisms in alveolar epithelial type I cells and any inability of type II progenitor cells to resist and repair epithelial injury are indicators that impaired response t

Interleukin-15 and Influenza Virus Infection in a Mouse Model of Chronic Obstructive Pulmonary Disease

pats.atsjournals.org - 4/29/12

Pharmacotherapeutic Approaches to Preventing Acute Exacerbations of Chronic Obstructive Pulmonary Disease

pats.atsjournals.org - 8/3/11

The significance of acute exacerbations in chronic obstructive pulmonary disease (AECOPDs) is increasingly appreciated. AECOPDs result in significant morbidity and mortality and are a significant driver of health care costs. Frequent AECOPDs are associated with poor quality of life and more rapid decline in lung function. As such, reducing their frequency or severity is a key paradigm of COPD therapy. Bronchodilators alone and in combination with inhaled corticosteroids are the current standards of ca

Genetic Factors and Interrelationships for Cancer Risk-Related Behaviors and Complex Traits

www.clinicaltrials.gov - 11/2/99

Conditions: AcquiredImmunodeficiencySyndrome; Alcoholism; HIVInfection; Neoplasm; Smoking
Intervention:
Sponsor: NationalCancerInstitute(NCI)
Completed - verified July 2004

A Study of Atvogen in Healthy Volunteers and HIV-Infected Patients Who Have No Symptoms of Infection

www.clinicaltrials.gov - 11/1/99

Condition: HIVInfections
Intervention: Drug:Ampligen
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Completed - verified August 1991

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FROM PHYSICIANS PRACTICE

Key Differences between FQHCs and RHCs
Chastity Werner, RHIT, June 13, 2013
FQHCs and RHCs take up a unique niche among physician practices. And that affects compensation and billing.

Improving Care Coordination in Your Practice
Susanne Madden, June 12, 2013
Practices are feverishly working to control the rising costs of healthcare - effective care coordination can help.

Refunding Overpayments: Two Options for Medical Practices
Ericka L. Adler, June 12, 2013
Medicare and Medicaid providers must return overpayments once identified. Here are two different refund approaches for practices to consider when necessary.

Four Easy Ways to Boost Patient Time of Service Collections
Aubrey Westgate, June 12, 2013
Simple ways your medical practice staff can increase the likelihood patients will pay when presenting for appointments.

iPad Alternatives for Mobile Physicians
Marisa Torrieri, June 11, 2013
As more physicians are seeing the merits of media tablets, the market is expanding, too.

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SEARCHMEDICA NEWS

SearchMedica News From a top search during the past week on SearchMedica

Unusual Inflammatory Triggers for Ulcerative Colitis

March 30, 2012

FEATURED SEARCH TERM: ulcerative colitis

To the possible triggers of bowel inflammation, add unexpected reactions to cosmetic procedures. Ulcerative colitis was one of the adverse reactions to an illicit cosmetic procedure in Mexico. Injection of foreign substances, mostly oils, led the 50 women in this case study to develop autoimmune disease, as well as non-specific autoimmune manifestations, all of which fit the model of Autoimmune/inflammatory Syndrome Induced by Adjuvants (ASIA).

RESULT: Human adjuvant disease induced by foreign substances: a new model of ASIA (Shoenfeld's syndrome)
Journal of the American College of Cardiology | Jan 10, 2012 (FREE FULL TEXT)

On the other hand, intentionally inducing and studying the inflammatory reaction could lead to useful treatment insights. In this study, experimentally induced hookworm infections in human volunteers suppressed pro-inflammatory cytokine production in the gut. The only previous report of intentionally induced hookworms in humans was an attempt to treat ulcerative colitis with whipworm. These researchers suggest that manipulating the anti-hookworm response may inspire new therapies for inflammatory diseases.

RESULT: Characterising the Mucosal and Systemic Immune Responses to Experimental Human Hookworm Infection
PLoS Pathogens | Feb 9, 2012 (FREE FULL TEXT)

MANAGE YOUR PRACTICE

When a Patient's Family Asks a Physician to Intervene

Physicians Practice - 6/19/13

When a Patient's Family Asks a Physician to Intervene

Blog | June 19, 2013 | Difficult Patients, Healthcare Careers, Law & Malpractice, Patient Relations

A Physicians Practice reader recently shared a dilemma he is facing in practice. Weigh in to help him best deal with this issue.

Avoiding Medical Practice Hiring Pitfalls

Physicians Practice - 6/18/13

Avoiding Medical Practice Hiring Pitfalls

Blog | June 19, 2013 | ACO, Healthcare Careers, Healthcare Reform, Hiring Firing, Staff

By Aubrey Westgate

Why prioritizing personality and cultural fit is becoming more important when hiring at medical practices.

More Effectively Schedule Patient Visits at Your Practice

Physicians Practice - 6/18/13

More Effectively Schedule Patient Visits at Your Practice

Blog | June 19, 2013 | Operations, Patient Relations, Productivity

By Carol Stryker

Effective patient visit scheduling is obviously not as easy as it seems. Here's how to ensure your practice makes smart scheduling decisions.

Vendor Relationships and Your Medical Practice

Physicians Practice - 6/18/13

Vendor Relationships and Your Medical Practice

Pearl | June 18, 2013 | Pearls, Managers Administrators, Operations

By Rosemarie Nelson

Vendor relationship management, done with purpose and thoughtfulness, can benefit any medical practice - large or small.

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